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更新時間:2022-01-27
The MAR1-5A3 monoclonal antibody reacts with mouse IFNAR-1 (IFN alpha/beta receptor subunit 1). IFNAR-1 is coexpressed with IFNAR-2 on nearly all cell types and together these two subunits make up the
The MAR1-5A3 monoclonal antibody reacts with mouse IFNAR-1 (IFN alpha/beta receptor subunit 1). IFNAR-1 is coexpressed with IFNAR-2 on nearly all cell types and together these two subunits make up the heterodimeric Type I IFN Receptor complex. Type I IFNs (IFN-α/β) bind to the Type I IFN Receptor complex to induce cellular responses including induction of anti-viral, anti-microbial, anti-tumor, and autoimmune responses as well as to regulate the activation, proliferation, and differentiation of many cell types. The MAR1-5A3 antibody has been shown to inhibit Type I IFN receptor signaling in vitro and in vivo.
產(chǎn)品名稱:InVivoMab anti-mouse IFNAR-1
反應(yīng)種屬:mouse
宿主來源:mouse
實驗應(yīng)用:in vivo IFNAR-1 blockade, in vitro IFNAR-1 blockade
同種型:IgG1, κ
免疫原:Extracellular domain of mouse IFNAR-1
克隆性:Monoclonal
克隆號:MAR1-5A3
產(chǎn)品濃度:Lot specific,typically between 4-11 mg/ml
保存溫度:Undiluted at 4°C in the dark
運(yùn)輸溫度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit
預(yù)期分子量:150 kDa
產(chǎn)品形式:液體
有效期:One year from the date of receipt if stored as recommended
產(chǎn)地:美國
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